CD BioSciences provides a variety of proteomics techniques to assist your GPCR research and drug development. Our proteomics platforms apply advanced proteomics methods to further our understanding of complex GPCR pathways associated with different diseases and diseases related to the absence of GPCR function.
Gel-based proteomics is the most versatile method for protein separation and quantification. It can be used for large-scale screening of protein expression, and has lower cost compared with gel-free proteomics.
Mass spectrometry-based gel-free proteomics, as a key technology for high-throughput identification and quantification of complex protein mixtures, may help to reveal unknown changes in protein interactions and assemblies involved in regulating cell and physiological processes.
Targeted proteomics is an emerging area of proteomics used for protein and peptide quantification, which has the advantages of high sensitivity, quantitative accuracy, reproducibility and multiplexing capabilities. It has a great potential for clinical applications.
Quantitative proteomics is a powerful approach used for quantify global changes in protein abundance and providing information about the physiological differences between samples. It plays an essential role for investigating the proteome of disease states.
Expression proteomics is used to study the quantitative differences in protein expression between samples that differ by some variable. It helps identify disease-specific proteins, that have the potential to be useful diagnostic markers or drug targets.
Interaction proteomics focuses on the analysis of binary protein interactions to proteome-wide protein interactions. Understanding protein interaction patterns in biological networks plays an essential role in understanding system-level biology.
Structural proteomics can be used to determine genome-wide atomic resolution three-dimensional protein structure, which is helpful to understand protein sequence/structure/function relationships and to reveal the binding sites of drugs on proteins.
Functional proteomics can elucidate the biological function of proteins at the proteome-wide level and define cellular mechanisms at the molecular level. It is a powerful tool to provide valuable information on target druggability.
Translational proteomics uses and complements multidisciplinary approaches untangle complex disease processes. It focuses on producing quantitative, standardized, reproducible, and scalable results to make a link between basic sciences and clinical practice.
Mass spectrometry (MS) has become an indispensable tool in proteomics to study protein expression, protein interaction and protein modification.
Two-Dimensional Gel Electrophoresis
Two-dimensional gel electrophoresis or 2-D electrophoresis is commonly used for protein separation and analysis of protein mixtures. It offers great flexibility and tunable resolution.
Isoelectric focusing (IEF) is used to separate a single unique protein from a complex mixture. It is also of great significance for to protein identification characterization.
Multidimensional liquid chromatography
Multidimensional liquid chromatography (MDLC) for proteomic studies has the advantage of being able to fully automate multidimensional LC-MS-MS-MS systems.
Nanoscale Liquid Chromatography
Nanoscale Liquid Chromatography (nano LC) is commonly used to separate peptides and proteins. It has enhanced sensitivity and automatic analysis capability.
Bioinformatics for Proteomics
Bioinformatics techniques allow for faster proteomics analysis and data storage. Bioinformatics-based proteomics can be applied in various fields.
We have established several advanced proteomics platforms to meet different needs.
We are dedicated to develop tailored GPCR proteomics solutions for specific requirements.
We have a professional scientific team with extensive experience in proteomics to help you with any technical questions.
We provide our customers with customized one-stop solutions to help them advance cutting-edge projects.
We deliver high-quality results under strict quality control and reliable data with traceable records.
Fast turnaround time
Our advanced techniques and effective scheduling systems allow our services to have a fast turnaround time.
If you are interested in our techniques or have any specific needs, please feel free to contact us for more details.