GPCR Structural Biology
Creative Biolabs provides a range of sophisticated techniques and access to state-of-the-art instruments to help our customers elucidate GPCR structure and function, and fully assist GPCR research and drug development.
Structural Biology Platforms
X-ray crystallography (XRC) is the most popular technique for protein structure determination. It is a powerful tool to determine the atomic and molecular structure of a protein crystal.
Electron crystallography, which combines quantitative electron diffraction and high (atomic) resolution electron microscopy with image processing, has become a powerful tool for membrane protein structure determination.
Electron microscopy (EM) is widely used to investigate the ultrastructure of proteins. Cryogenic electron microscopy (cryo-EM) allows to observe protein structures as close as possible to their native state.
Nuclear Magnetic Resonance Spectroscopy
Nuclear magnetic resonance (NMR) Spectroscopy is useful in the study of both structure and dynamics of proteins and their complexes in solution. It helps to elucidate the relationship between structure, dynamics, and function.
Native Mass Spectrometry
Native mass spectrometry (MS) is particularly powerful in defining the topological structure, dynamics, and structural properties of protein complexes. It can be a bridge between structural biology and interactomics.
Electron Paramagnetic Resonance
Electron paramagnetic resonance (EPR), as complementary to existing biophysical methods, is a powerful tool to collect the unique structure and dynamic information of membrane proteins.
Neutron Protein Crystallography
Neutron protein crystallography is a powerful tool to locate hydrogen atom directly in protein structure without inducing radiation damage in protein crystals. It is complementary to ultra-high-resolution X-ray diffraction.
Ultrafast Laser Spectroscopy
Ultrafast laser spectroscopy, a new technique for the characterization of the relationship between protein structure and properties, is helpful to reveal the potential sequence-structure relationship for protein assembly and aggregation.
Computational Structural Biology
Computational structural biology has emerged as a powerful tool for the identification of protein structure and dynamics. It aims at illuminating sequence-structure-function relationships by using theoretical models and molecular stimulation.
We have established several advanced structural biology platforms to meet different needs.
We are dedicated to develop tailored solutions based on GPCR structural biology for specific requirements.
We have a professional scientific team with extensive experience in structural biology to help you with any technical questions.
We provide our customers with customized one-stop solutions to help them advance cutting-edge projects.
We deliver high-quality results under strict quality control and reliable data with traceable records.
Fast turnaround time
Our advanced techniques and effective scheduling systems allow our services to have a fast turnaround time.
If you are interested in our techniques or have any specific needs, please feel free to contact us for more details.