Pharmacogenomics of GPCRs
Pharmacogenomics is a combination of pharmacology and genomics. It is a genome-wide association approach to deal with the effects of multiple genes on drug response. As the primary therapeutic targets, G protein-coupled receptors (GPCRs) have always been the focus of pharmacogenomics. GPCR pharmacogenomic data makes it possible to routinely evaluate GPCR variants for predicting drug response, disease risk, and potential adverse drug reactions.
Creative Biolabs provides pharmacogenomic solutions based on our advanced genetic platforms to accelerate GPCR research and drug development. Our experienced scientific team will work closely with our customers to help them select the right solution for their specific needs.
Genome-Wide Analysis of Genetic Variations
Genome-wide analysis of genetic variation is the core issue in the field of pharmacogenomics. It helps to reveal the relationship between genetic variation and drugs, and to elucidate their mechanisms of action.
Drug Metabolizing Enzymes Profiling
Genetic polymorphisms of drug metabolizing enzymes (DMEs) are important causes for lack of drug response and adverse drug reactions. More targeted research on the genes encoding DMEs can provide more information for variations in drug response.
Genome-Wide Association Studies
Genome-wide association studies (GWAS) can be used to examine drug metabolism, toxicity and efficacy. It provides an unbiased approach to discover the underlying mechanisms and pathways of human diseases and drug responses.
Real-Time PCR Solutions
Pharmacogenomics is becoming a powerful tool for precision medicine. Real-time PCR provides a quick, accurate and low-cost approach for pharmacogenomics research. The combination with high-throughput technology can further reduce turnaround time.
Next-generation sequencing plays an important role in the discovery of novel and uncharacterized GPCR variants. Several computational tools are available for function prediction. Effective pharmacodynamic evaluation of these variants is essential for the development of novel drugs.
Microarrays can provide a global view of the genome. They can be used to collect and analyze vast amounts of data, ranging from identifying markers to discovering new drug targets. Microarrays have become critical tools in the field of pharmacogenomics.
We have established several advanced platforms for pharmacogenomics to meet different needs.
We are dedicated to develop tailored pharmacogenomic solutions for GPCRs.
We have a professional scientific team with extensive experience in pharmacogenomics to help you with any technical questions.
We provide our customers with customized one-stop solutions to help them advance cutting-edge projects.
We deliver high-quality results under strict quality control and reliable data with traceable records.
Fast turnaround time
Our advanced techniques and effective scheduling systems allow our services to have a fast turnaround time.
If you are interested in our techniques or have any specific needs, please feel free to contact us for more details.