Applications

• Applications:
• Western Blot, Immunohistochemistry

Specification

• Description:
• ADRB2 Rabbit Polyclonal Antibody is raised against synthetic peptide (conjugated with KLH) corresponding to residues surrounding S261 of human ADRB2.

• Molecular Weight (kDa):
• 46.6 (Transfected lysate)

• Form:
• Liquid

• Purification:
• Protein A purification

• Storage Buffer:
• In PBS (0.09% Sodium Azide)

• Storage:
• Short term storage: 4°C.
  Long term storage: -20°C or lower.
  Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name:
• ADRB2

• Gene Description:
• ADRB2 (Adrenoceptor Beta 2) is a Protein Coding gene. This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This receptor is also a transcription regulator of the alpha-synuclein gene, and together, both genes are believed to be associated with risk of Parkinson's Disease. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity, type 2 diabetes and cardiovascular disease. [provided by RefSeq, Oct 2019]

• Protein Accession Number:
• P07550; NP_000015