Applications

• Applications:
• Western Blot, Immunofluorescence, Enzyme-Linked Immunoabsorbent Assay

Specification

• Description:
• ADRB2 Rabbit Polyclonal Antibody is raised against synthetic peptide corresponding to the C-terminus of human ADRB2. This antibody is specific.

• Molecular Weight (kDa):
• 46.6 (Transfected lysate)

• Form:
• Liquid

• Storage Buffer:
• In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% Sodium Azide)

• Storage:
• Store at -20°C or lower.
  Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name:
• ADRB2

• Gene Description:
• ADRB2 (Adrenoceptor Beta 2) is a Protein Coding gene. This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This receptor is also a transcription regulator of the alpha-synuclein gene, and together, both genes are believed to be associated with risk of Parkinson's Disease. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity, type 2 diabetes and cardiovascular disease. [provided by RefSeq, Oct 2019]

• Protein Accession Number:
• P07550