ADRB2 Rabbit Polyclonal Antibody (D01)
For Research Use Only. Not For Clinical Use.
Catalog Number: PAB-R0014
Host: Rabbit
Reactivity: Human, Mouse
Product Size | Price |
---|---|
100 μL | Online Inquiry |
Applications
- Applications:
- Western Blot, Immunoprecipitation
Specification
- Description:
- ADRB2 Rabbit Polyclonal Antibody (D01) is raised against a full-length human ADRB2 protein (1 a.a. -413 a.a.).
- Molecular Weight (kDa):
- 46.6 (Transfected lysate)
- Sequence:
- MGQPGNGSAFLLAPNRSHAPDHDVTQQRDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
- Storage Buffer:
- No additive
- Storage:
-
Store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.
Gene Information
- Gene Name:
- ADRB2
- Gene Description:
- ADRB2 (Adrenoceptor Beta 2) is a Protein Coding gene. This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This receptor is also a transcription regulator of the alpha-synuclein gene, and together, both genes are believed to be associated with risk of Parkinson's Disease. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity, type 2 diabetes and cardiovascular disease. [provided by RefSeq, Oct 2019]
- GenBank Accession Number:
- NM_000024
- Protein Accession Number:
- NP_000015.1