Applications

• Applications:
• Western Blot (1:1000), Immunohistocemistry (1:50-100)

Specification

• Description:
• CCBP2 Rabbit Polyclonal Antibody is raised against synthetic peptide (conjugated with KLH) corresponding to the N-terminus of human CCBP2.

• Form:
• Liquid

• Purification:
• Protein G purification

• Storage Buffer:
• In PBS (0.09% Sodium Azide)

• Storage:
• Short term storage: 4°C.
  Long term storage: -20°C or lower.
  Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name:
• CCBP2

• Gene Description:
• CCBP2 (Chemokine Binding Protein 2) is a Protein Coding gene.This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes. [provided by RefSeq, Jul 2008]

• Protein Accession Number:
• NP_001287