Applications

• Applications:
• Western Blot (0.75 μg/mL), Immunohistochemistry (0.5-1 μg/mL)

Specification

• Description:
• CCR6 Rabbit Polyclonal Antibody is raised against synthetic peptide corresponding to amino acids at N-terminus of human CCR6.

• Isotype:
• IgG

• Molecular Weight (kDa):
• 42.4 (Theoretical)

• Form:
• Lyophilized

• Purification:
• Affinity purification

• Storage Buffer:
• Lyophilized from 0.9 mg NaCl, 0.2 mg Na2HPO4 (5 mg BSA, 0.05 mg Sodium Azide, 0.05 mg Thimerosal)

• Storage:
• Store at -20°C or lower.
  Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name:
• CCR6

• Gene Description:
• CCR6 (C-C Motif Chemokine Receptor 6) is a Protein Coding gene. This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]