Applications

• Applications:
• Immunofluorescence (1:100-1:500), Enzyme-Linked Immunoabsorbent Assay (1:10000)

Specification

• Description:
• CELSR1 Rabbit Polyclonal Antibody is raised against synthetic peptide corresponding to amino acids 921-970 of human CELSR1 and can detect the endogenous level of total CELSR1 protein..

• Molecular Weight (kDa):
• 329

• Form:
• Liquid

• Purification:
• Affinity chromatography

• Storage Buffer:
• In PBS (without Mg2+ and Ca2+), pH 7.4 (150mM NaCl, 0.02% Sodium Azide, 50% glycerol).

• Storage:
• Store at -20°C or lower.
  Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name:
• CELSR1

• Gene Description:
• CELSR1 (Cadherin EGF LAG Seven-Pass G-Type Receptor 1) is a Protein Coding gene. The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. This particular member is a developmentally regulated, neural-specific gene which plays an unspecified role in early embryogenesis. [provided by RefSeq, Jul 2008]

• Protein Accession Number:
• Q9NYQ6