Applications

• Applications:
• Western Blot (1:500), Immunoprecipitation (1:250)

Specification

• Description:
• CXCR3 Rabbit Polyclonal Antibody is raised against synthetic peptide corresponding to amino acids 8-33 of human CXCR3.

• Form:
• Liquid

• Sequence:
• VETFGTTSYYDDVGLLCEKADTRALM

• Storage Buffer:
• In buffer containing 0.02% Sodium Azide

• Storage:
• Store at -20°C or lower.
  Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name:
• CXCR3

• Gene Description:
• CXCR3 (C-X-C Motif Chemokine Receptor 3) is a protein coding gene. This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716). [provided by RefSeq, Jun 2011]