Applications

• Applications:
• Western Blot (1 μg/mL), Immunohistochemistry (2 μg/mL)

Specification

• Description:
• CXCR4 Rabbit Polyclonal Antibody is raised against synthetic peptide corresponding to amino acids at N-terminus of human CXCR4.

• Isotype:
• IgG

• Molecular Weight (kDa):
• 39.7, 40.2 (Theoretical)

• Form:
• Lyophilized

• Purification:
• Affinity purification

• Storage Buffer:
• Lyophilized from 0.9 mg NaCl, 0.2 mg Na2HPO4 (5 mg BSA, 0.05 mg Sodium Azide, 0.05 mg Thimerosal)

• Storage:
• Store at -20°C or lower.
  Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name:
• CXCR4

• Gene Description:
• CXCR4 (C-X-C Motif Chemokine Receptor 4) is a protein coding gene. This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]