Applications

• Applications:
• Immunohistochemistry (15 μg/mL)

Specification

• Description:
• FZD7 Rabbit Polyclonal Antibody is raised against synthetic peptide (conjugated with KLH) corresponding to the C-terminal domain of human FZD7.

• Form:
• Liquid

• Purification:
• Immunoaffinity purification

• Storage Buffer:
• In PBS (0.09% Sodium Azide)

• Storage:
• Short term storage: 4°C.
  Long term storage: -20°C or lower.
  Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name:
• FZD7

• Gene Description:
• FZD7 (Frizzled Class Receptor 7) is a protein coding gene. Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008]

• Protein Accession Number:
• O75084