Applications

• Applications:
• Immunohistochemistry (18 μg/mL)

Specification

• Description:
• GPBAR1 Rabbit Polyclonal Antibody is raised against synthetic peptide corresponding to 16 amino acid at cytoplasmic domain of human GPBAR1.

• Form:
• Liquid

• Purification:
• Immunoaffinity chromatography

• Storage Buffer:
• In PBS (0.09% Sodium Azide)

• Storage:
• Short term storage: 4°C.
  Long term storage: -20°C or lower.
  Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name:
• GPBAR1

• Gene Description:
• GPBAR1 (G Protein-Coupled Bile Acid Receptor 1) is a Protein Coding gene. This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]

• Protein Accession Number:
• Q8TDU6