Applications

• Applications:
• Western Blot (1:1000), Immunohistochemistry (1:10-1:50)

Specification

• Description:
• LGR5 Rabbit Polyclonal Antibody is raised against synthetic peptide (conjugated with KLH) corresponding to amino acids 451-480 at internal region of human LGR5.

• Form:
• Liquid

• Purification:
• Ammonium sulfate precipitation

• Storage Buffer:
• In PBS (0.09% Sodium Azide)

• Storage:
• Short term storage: 4°C.
  Long term storage: -20°C or lower.
  Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name:
• LGR5

• Gene Description:
• LGR5 (Leucine Rich Repeat Containing G Protein-Coupled Receptor 5) is a Protein Coding gene. The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]

• Protein Accession Number:
• NP_003658; O75473