CHO-K1/CRE-bla/ADORA2A Division Arrested Assay Kit

CHO-K1/CRE-bla/ADORA2A Division Arrested Assay Kit

For Research Use Only. Not For Clinical Use.

Catalog Number: DAC0001

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  • Cell Line:
  • CHO-K1
  • GPCR Family:
  • Adenosine Receptors
  • Gene Name:
  • GenBank Accession Number:
  • NM_000675
  • Cell State:
  • Division-Arrested Cells
  • Detection Method:
  • Fluorescent
  • Component:
  • This assay kit includes sufficient cells and substrate to analyze 1 × 384-well plate
  • Shipping Condition:
  • Dry Ice
  • Storage:
  • Store in liquid nitrogen immediately upon receipt or thaw for immediate use.
  • Population Status:
  • Single Cell Clone Origin
  • Receptor Type:
  • BLA (Beta-Lactamase)


  • CHO-K1/CRE-bla/ADORA2A Division Arrested Cells are stable recombinant cells expressing the human Adenosine Receptor A2A (ADORA2A). Under the control of the Cyclic AMP Response Element (CRE) response element, these cells can stably express the beta-lactamase (bla) reporter gene. Using a low-dose treatment of Mitomycin-C, these cells are irreversibly division arrested, but without apparent toxicity or change in cellular signal transduction. These cells have been functionally validated and tested under variable conditions. ADORA2A has been shown to he involved in many biological functions, such as the regulation of blood pressure, pain and inflammation , inhibition of platelet aggregation, and contributes to ischemic brain damage.