Specification

• Cell Line:
• CHO-K1

• GPCR Family:
• VIP Receptors

• Gene Name:
• VPAC1

• Assay Target Class:
• GPCR

• GenBank Accession Number:
• NM_004624

• Detection Method:
• Fluorescent

• Population Status:
• Single Cell Clone Origin

• Shipping Condition:
• Dry Ice

• Storage:
• Should be stored in liquid nitrogen immediately upon receipt.

• Technique:
• FRET

Description

• We have different stable recombinant cell lines that express a variety of GPCRs for binding and functional assays.

Detailed Information

• CHO-K1/CRE-bla/VPAC1 is a stable recombinant human cell line expressing the human Vasoactive intestinal peptide/pituitary adenylate cyclase activating polypeptide receptor 1 (VPAC1). Under the control of the Cyclic AMP Response Element (CRE) response element, this cell line can stably express the beta-lactamase (bla) reporter gene. This cell line has been functionally validated and tested under variable conditions. VPAC1 has been implicated in multiple disorders, such as rheumatoid arthritis, Parkinson's disease, Crohn's disease, autoimmune diabetes, and HIV infection.