Specification

• Cell Line:
• HEK293T

• GPCR Family:
• Endothelin Receptors

• Gene Name:
• EDNRA

• Assay Target Class:
• GPCR

• GenBank Accession Number:
• NM_001957

• Detection Method:
• Fluorescent

• Population Status:
• Single Cell Clone Origin

• Shipping Condition:
• Dry Ice

• Storage:
• Should be stored in liquid nitrogen immediately upon receipt.

• Technique:
• FRET

Description

• We have different stable recombinant cell lines that express a variety of GPCRs for binding and functional assays.

Detailed Information

• HEK293/NFAT-bla/EDNRA is a stable recombinant human cell line expressing the human Endothelin Type A Recpetor (EDNRA). Under the control of the Nuclear Factor of Activated T-cells (NFAT) response element, this cell line can stably express the beta-lactamase (bla) reporter gene. This cell line has been functionally validated and tested under variable conditions. The EDNRA receptor mediates the signal transduction of several endothelin proteins, which are involved in the regulation of several key biological processes, such as the the production of some hormones, development and function of blood vessels, and the stimulation of cell growth and division. The defects of EDNRB are related to various diseases, including cancer, and cardiovascular disorders