Properties

• Target:
• Free Fatty Acid Receptor 1 (GPR40)

• CAS Number:
• 1291087-14-3

• Chemical Name:
• (S)-3-(4-((4'-(trifluoromethyl)biphenyl-3-yl)methoxy)phenyl)hex-4-ynoic acid calcium salt

• Storage:
• Store at +4°C

• Molecular Formula:
• C26H20F3O3.½Ca

• Molecular Weight (kDa):
• 457.47

• Soluble:
• DMSO

Description

• Description:
• Partial free fatty acid receptor 1 (FFA1/GPR40) agonist

Biological Activity

• Biological Activity:
• AMG 837 calcium salt is an orally bioavailable partial agonist of the free fatty acid receptor 1 (GPR40). It has potential utility for the treatment of type 2 diabetes.