Properties

• Target:
• MRGPR

• CAS Number:
• 858350-62-6

• Chemical Name:
• (1'-(but-3-enyl)-5-chlorospiro[indoline-3,4'-piperidine]-1-yl)(2,6-difluorophenyl)methanone

• Molecular Formula:
• C23H23ClF2N2O

• Molecular Weight (kDa):
• 416.89

• Soluble:
• 0.1N HCl(aq) and DMSO

Description

• Description:
• Mas-related G-protein coupled receptor inverse agonist

Biological Activity

• Biological Activity:
• AR 244555 is a Mas-related G-protein coupled receptor inverse agonist. In rat hearts, it can cause a modest but significant increase in coronary flow in without causing arrhythmias.