Properties

• Target:
• CCR2

• CAS Number:
• 871313-59-6

• Chemical Name:
• 3-[(1S)-1-(3,4-Difluorophenyl)propyl]-2,3-dihydro-5-(5-isoxazolyl)-2-thioxo-1H-imidazole-4-carboxylic acid methyl ester

• Storage:
• Store at +4°C

• Molecular Formula:
• C17H15F2N3O3S

• Molecular Weight (kDa):
• 379.38

• Soluble:
• DMSO and Ethanol

Description

• Description:
• Potent and selective human chemokine receptor CCR2 antagonist

Biological Activity

• Biological Activity:
• JNJ 27141491 is a potent and selective human chemokine receptor CCR2 antagonist. It is noncompetitive and orally active.