Properties

• Target:
• CRF1 Receptor

• CAS Number:
• 1782228-59-4

• Chemical Name:
•  (7S)-6-(Cyclopropylmethyl)-2-(2,4-dichlorophenyl)-7-ethyl-7,8-dihydro-4-methyl-6H-1,3,6,8a-tetraazaacenaphthylene hydrochloride

• Storage:
• Desiccate at RT

• Molecular Formula:
• C21H22Cl2N4.HCl

• Molecular Weight (kDa):
• 437.79

• Soluble:
• Water and DMSO

Description

• Description:
• Potent and selective CRF1 receptor antagonist

Biological Activity

• Biological Activity:
• NBI 35965 hydrochloride is a potent and selective Corticotropin-Releasing hormone receptor 1 (CRF1) antagonist. It is orally active and brain penetrant.