Properties

• Target:
• CRF1 Receptor

• CAS Number:
• 321839-75-2

• Chemical Name:
• (S)-4-(2-chloro-4-methoxy-5-methylphenyl)-N-(2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl)-5-methyl-N-(prop-2-ynyl)thiazol-2-amine hydrochloride

• Storage:
• Store at -20°C

• Molecular Formula:
• C27H28ClFN2OS.HCl

• Molecular Weight (kDa):
• 519.5

• Soluble:
• DMSO

Description

• Description:
• Potent and selective CRF1 receptor antagonist

Biological Activity

• Biological Activity:
• SSR 125543A is a potent and selective Corticotropin-Releasing hormone receptor 1 (CRF1) antagonist. It is orally active and brain penetrant.