Properties

• Target:
• PAR2

• CAS Number:
• 1252806-86-2

• Chemical Name:
• N-((S)-3-cyclohexyl-1-((2S,3S)-1-(2,3-dihydrospiro[indene-1,4'-piperidine]-1'-yl)-3-methyl-1-oxopentan-2-ylamino)-1-oxopropan-2-yl)isoxazole-5-carboxamide

• Storage:
• Store at -20°C

• Molecular Formula:
• C32H44N4O4

• Molecular Weight (kDa):
• 548.72

• Soluble:
• DMSO

Description

• Description:
• Selective PAR2 antagonist

Biological Activity

• Biological Activity:
• GB 83 is a selective protease-activated receptor-2 (PAR2) antagonist. It can reversibly inhibit the activation of PAR2 by both proteases and other PAR2 agonists.