Properties

• Target:
• S1P2 Receptor

• CAS Number:
• 383150-41-2

• Chemical Name:
• 1-[1,3-Dimethyl-4-(2-methylethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]-4-(3,5-dichloro-4-pyridinyl)-semicarbazide

• Storage:
• Store at +4°C

• Molecular Formula:
• C17H19N7OCl2

• Molecular Weight (kDa):
• 408.29

• Soluble:
• DMSO and Ethanol

Description

• Description:
• Selective S1P2 receptor antagonist

Biological Activity

• Biological Activity:
• JTE 013 is a sphingosine-1-phosphate receptor 2 (S1P2R) antagonist. It can inhibit the binding of S1P to human S1P2 receptors and enhance S1P-induced angiogenesis in vivo.