Properties

• Target:
• NK1 Receptor

• CAS Number:
• 290297-26-6

• Chemical Name:
• 2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethyl-N-(6-(4-methylpiperazin-1-yl)-4-o-tolylpyridin-3-yl)propanamide

• Storage:
• Store at -20°C

• Molecular Formula:
• C30H32F6N4O

• Molecular Weight (kDa):
• 578.59

• Soluble:
• 0.1N HCl(aq) and DMSO

Description

• Description:
• Selective NK1 receptor antagonist

Biological Activity

• Biological Activity:
• Netupitant is a highly selective neurokinin 1 (NK1) receptor antagonist. It is an approved drug in combination with Palonosetron, which can be used to prevent nausea and vomiting (CINV) induced by chemotherapy.