Properties

• Target:
• GRK2/3

• CAS Number:
• 865608-11-3

• Chemical Name:
• 3-[[[4-Methyl-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]methyl]amino]-N-[[2-(trifluoromethyl)phenyl]methyl]benzamide

• Storage:
• Store at -20°C

• Molecular Formula:
• C24H21F3N6O

• Molecular Weight (kDa):
• 466.46

• Soluble:
• DMSO and Ethanol

Description

• Description:
• Potent and selective GRK2/3 inhibitor

Biological Activity

• Biological Activity:
• CMPD101 is a potent and selective GRK2/3 inhibitor. It can reduce the desensitization and internalization of μ-opioid receptors induced by DAMGO.