Applications

• Applications:
• Flow Cytometry

Specification

• Clone:
• MEM-180

• Description:
• CD97 Mouse Monoclonal Antibody, FITC is raised against native purified CD97 from PHA-activated peripheral blood leucocytes. It can recognize an unique epitope on CD97.

• Isotype:
• IgG1

• Molecular Weight (kDa):
• 75-85 (Theoretical)

• Form:
• Liquid

• Storage Buffer:
• In PBS (0.2% BSA, 0.09% Sodium Azide)

• Storage:
• Store 4°C. Do not freeze.
  Avoid prolonged exposure to light.
  Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name:
• CD97

• Gene Description:
• CD97 (CD97 molecule) is a protein-coding gene. This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19. [provided by RefSeq, Jun 2011]