Applications

• Applications:
• Western Blot, Immunofluorescence, Enzyme-Linked Immunoabsrbent Assay

Specification

• Clone:
• 3C7

• Description:
• CNR2 Mouse Monoclonal Antibody (M01) is raised against a partial recombinant CNR2 (302 a.a. - 360 a.a.) with GST tag. The molecular weight of the GST tag is 26 kDa.

• Isotype:
• IgG1 kappa

• Molecular Weight (kDa):
• 32.12 (Immunogen)

• Sequence:
• RSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC

• Storage Buffer:
• In 1× PBS, pH 7.4

• Storage:
• Store at -20°C or lower.
  Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name:
• CNR2

• Gene Description:
• CNR2 (Cannabinoid Receptor 2) is a protein coding gene. The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors. [provided by RefSeq, Jul 2008]

• GenBank Accession Number:
• NM_001841.1

• Protein Accession Number:
• NP_001832.1