Applications

• Applications:
• Western Blot, Enzyme-Linked Immunoabsorbent Assay

Specification

• Description:
• GPR151 Rabbit Monoclonal Antibody is raised against a synthetic peptide of human GPR151.

• Isotype:
• IgG

• Purification:
• Protein A

• Storage Buffer:
• In 1× PBS, pH 7.4

• Storage:
• Short term storage: 4°C.
  Long term storage: -20°C or lower.
  Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name:
• GPR151

• Gene Description:
• GPR151 (G Protein-Coupled Receptor 151) is a Protein Coding gene. Diseases associated with GPR151 include Brachial Plexus Lesion. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity. An important paralog of this gene is RXFP3. This gene encodes an orphan member of the class A rhodopsin-like family of G-protein-coupled receptors (GPCRs). Within the rhodopsin-like family, this gene is a member of the SOG subfamily that includes somatostatin, opioid, galanin, and kisspeptin receptors. The orthologous mouse gene has a restricted pattern of neuronal expression which is induced following nerve injury. All GPCRs have a transmembrane domain that includes seven transmembrane alpha-helices. A general feature of GPCR signaling is the agonist-induced conformational change in the receptor, leading to activation of the heterotrimeric G protein. The activated G protein then binds to and activates numerous downstream effector proteins, which generate second messengers that mediate a broad range of cellular and physiological processes. [provided by RefSeq, Jul 2017]