Applications

• Applications:
• Western Blot (0.1-0.3 μg/mL), Enzyme-Linked Immunoabsorbent Assay (1:32000)

Specification

• Description:
• CNR1 Goat Polyclonal Antibody is raised against a synthetic peptide corresponding to human CNR1. This antibody has the potential to recognize both reported isoforms.

• Molecular Weight (kDa):
• 52.9, 45.9 (Theoretical)

• Form:
• Liquid

• Concentration:
• 0.5 mg/mL

• Sequence:
• C-HTSEDGKVQVTRPDQ

• Purification:
• Antigen affinity purification

• Storage Buffer:
• In Tris saline, pH 7.3 (0.5% BSA, 0.02% Sodium Azide)

• Storage:
• Store at -20°C or lower.
  Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name:
• CNR1

• Gene Description:
• CNR1 (Cannabinoid Receptor 1) is a Protein Coding gene. This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. [provided by RefSeq, May 2009]

• Protein Accession Number:
• NP_057167.2; NP_149421.1