Applications

• Applications:
• Western Blot (0.3-1 μg/mL), Enzyme-Linked Immunoabsorbent Assay (1:64000)

Specification

• Description:
• FZD7 Goat Polyclonal Antibody is raised against a synthetic peptide corresponding to human FZD7.

• Molecular Weight (kDa):
• 63.6 (Theoretical)

• Form:
• Liquid

• Concentration:
• 0.5 mg/mL

• Sequence:
• C-RFYHRLSHSSKGET

• Purification:
• Antigen affinity purification

• Storage Buffer:
• In Tris saline, pH 7.3 (0.5% BSA, 0.02% Sodium Azide)

• Storage:
• Store at -20°C or lower.
  Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name:
• FZD7

• Gene Description:
• FZD7 (Frizzled Class Receptor 7) is a Protein Coding gene. Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008]

• Protein Accession Number:
• NP_0.03498.1