Applications

• Applications:
• Western Blot (1-3 μg/mL), Immunohistochemistry (3 μg/mL), Enzyme-Linked Immunoabsorbent Assay (1:32000)

Specification

• Description:
• FZD8 Goat Polyclonal Antibody is raised against a synthetic peptide corresponding to human FZD8.

• Molecular Weight (kDa):
• 73.3 (Theoretical)

• Form:
• Liquid

• Concentration:
• 0.5 mg/mL

• Sequence:
• C-SYPKQMPLSQV

• Purification:
• Antigen affinity purification

• Storage Buffer:
• In Tris saline, pH 7.3 (0.5% BSA, 0.02% Sodium Azide)

• Storage:
• Store at -20°C or lower.
  Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name:
• FZD8

• Gene Description:
• FZD8 (Frizzled Class Receptor 8) is a Protein Coding gene. This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq, Jul 2008]

• Protein Accession Number:
• NP_114072.1