Applications

• Applications:
• Enzyme-Linked Immunoabsorbent Assay (1:1000)

Specification

• Description:
• HTR2A Goat Polyclonal Antibody is raised against synthetic peptide corresponding to human HTR2A.

• Molecular Weight (kDa):
• 52.6 (Theoretical)

• Form:
• Liquid

• Concentration:
• 0.5 mg/mL

• Sequence:
• KNSKQDAKTTDNDCS

• Purification:
• Antigen affinity purification

• Storage Buffer:
• In Tris saline, pH 7.3 (0.5% BSA, 0.02% Sodium Azide)

• Storage:
• Store at -20°C or lower.
  Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name:
• HTR2A

• Gene Description:
• HTR2A (5-Hydroxytryptamine Receptor 2A) is a Protein Coding gene. This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

• Protein Accession Number:
• NP_000612.1