Applications

• Applications:
• Western Blot (0.1-0.3 μg/mL), Enzyme-Linked Immunoabsorbent Assay (1:16000)

Specification

• Description:
• PTGER4 Goat Polyclonal Antibody is raised against synthetic peptide corresponding to human PTGER4.

• Molecular Weight (kDa):
• 53.1 (Theoretical)

• Form:
• Liquid

• Concentration:
• 0.5 mg/mL

• Sequence:
• C-LEREVSKNPDLQA

• Purification:
• Antigen affinity purification

• Storage Buffer:
• In Tris saline, pH 7.3 (0.5% BSA, 0.02% Sodium Azide)

• Storage:
• Store at -20°C or lower.
  Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name:
• PTGER4

• Gene Description:
• PTGER4 (Prostaglandin E Receptor 4) is a Protein Coding gene. The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq, Jul 2008]

• Protein Accession Number:
• NP_000949.1